Chiung-Yuan Ko Selected Research

CCAAT-Enhancer-Binding Protein-delta

1/2021	CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma.
7/2019	CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation.
1/2018	Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation.
11/2017	Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia.
11/2016	Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury.
11/2015	HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells.
3/2015	CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer's disease.
2/2015	Increase of zinc finger protein 179 in response to CCAAT/enhancer binding protein delta conferring an antiapoptotic effect in astrocytes of Alzheimer's disease.
1/2015	Biological roles of CCAAT/Enhancer-binding protein delta during inflammation.
2/2012	CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells.

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Chiung-Yuan Ko Research Topics

Disease

13	Neoplasms (Cancer) 01/2021 - 11/2008
10	Glioblastoma (Glioblastoma Multiforme) 03/2022 - 10/2017
5	Glioma (Gliomas) 01/2021 - 11/2016
5	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 01/2014
4	Brain Neoplasms (Brain Tumor) 01/2021 - 04/2018
4	Inflammation (Inflammations) 01/2021 - 02/2012
2	Leukemia 11/2017 - 02/2015
2	Amyloid Plaque 02/2015 - 01/2014
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2010 - 11/2008
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Astrocytoma (Pilocytic Astrocytoma) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Neuroinflammatory Diseases 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Infections 01/2017
1	Spinal Cord Injuries (Spinal Cord Injury) 11/2016
1	Gliosis 11/2016
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2016
1	Liver Neoplasms (Liver Cancer) 11/2015
1	Hepatocellular Carcinoma (Hepatoma) 11/2008
1	Virus Diseases (Viral Diseases) 05/2002

Drug/Important Bio-Agent (IBA)

12	CCAAT-Enhancer-Binding Protein-deltaIBA 01/2021 - 11/2008
9	Temozolomide (Temodar)FDA LinkGeneric 03/2022 - 10/2017
5	Transcription Factors (Transcription Factor)IBA 01/2021 - 02/2015
5	Proteins (Proteins, Gene)FDA Link 09/2019 - 01/2014
4	Dehydroepiandrosterone (DHEA)IBA 01/2021 - 04/2019
3	NeurosteroidsIBA 01/2021 - 04/2019
3	MethyltransferasesIBA 04/2019 - 11/2008
2	Pharmaceutical PreparationsIBA 01/2021 - 11/2017
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021 - 04/2019
2	Vorinostat FDA Link 01/2021 - 11/2016
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 11/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 01/2018
2	RNA (Ribonucleic Acid)IBA 04/2018 - 01/2017
2	Amyloid (Amyloid Fibrils)IBA 01/2018 - 01/2014
2	Messenger RNA (mRNA)IBA 01/2016 - 11/2008
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2022
1	Pregnanolone (Allopregnanolone)IBA 01/2022
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021
1	Aromatase (CYP19)IBA 01/2021
1	Histone Deacetylase InhibitorsIBA 01/2021
1	Histone Deacetylase 6IBA 01/2021
1	MPT0B291IBA 01/2021
1	AndrogensIBA 01/2020
1	CurcuminIBA 01/2020
1	Glutathione PeroxidaseIBA 01/2020
1	Androgen Receptors (Androgen Receptor)IBA 01/2020
1	SteroidsIBA 09/2019
1	abirateroneIBA 09/2019
1	Hormones (Hormone)IBA 09/2019
1	NucleolinIBA 04/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Amyloid beta-PeptidesIBA 01/2018
1	Bortezomib (Velcade)FDA Link 11/2017
1	MicroRNAs (MicroRNA)IBA 11/2017
1	superoxide dismutase 2IBA 10/2017
1	RNA IsoformsIBA 01/2017
1	Viral ProteinsIBA 01/2017
1	CateninsIBA 01/2017
1	ClathrinIBA 01/2017
1	Histone Deacetylases (Histone Deacetylase)IBA 11/2016
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2016
1	Decitabine FDA Link 11/2015
1	Thrombospondin 1IBA 03/2015
1	Promyelocytic Leukemia Zinc Finger ProteinIBA 02/2015
1	Insulin-Like Growth Factor Binding Protein 3IBA 02/2015
1	Biological ProductsIBA 01/2015
1	CCAAT-Enhancer-Binding ProteinsIBA 01/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014
1	CytokinesIBA 01/2014
1	glycoprotein 41IBA 05/2002
1	Glycoproteins (Glycoprotein)IBA 05/2002
1	Amino Acids FDA Link 05/2002

Therapy/Procedure

4	Therapeutics 01/2022 - 12/2010
3	Radiotherapy 01/2021 - 04/2018
3	Drug Therapy (Chemotherapy) 01/2021 - 10/2017
1	Aftercare (After-Treatment) 01/2020
1	Transplantation 09/2019
1	CARE protocol 04/2018